Parkinson's disease : in vivo assessment of disease progression using positron emission tomography
Identifieur interne : 002B09 ( Main/Exploration ); précédent : 002B08; suivant : 002B10Parkinson's disease : in vivo assessment of disease progression using positron emission tomography
Auteurs : WING LOK AU [Canada] ; John R. Adams [Canada] ; André R. Troiano [Canada] ; A. Jon Stoessl [Canada]Source :
- Molecular brain research [ 0169-328X ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
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Abstract
Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). Furthermore, it allows the in vivo assessment of disease progression and the evaluation of treatment interventions. In this review, we shall discuss some of the issues and concerns that arise with the use of PET as a surrogate marker of disease progression in Parkinson's disease.
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Jon Stoessl</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Pacific Parkinson's Research Centre, University of British Columbia, Vancouver Hospital and Health Sciences Centre, Purdy Pavilion, 2221 Wesbrook Mall</s1><s2>Vancouver, BC, V6T 2B5</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Vancouver, BC, V6T 2B5</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Molecular brain research</title><title level="j" type="abbreviated">Mol. brain res.</title><idno type="ISSN">0169-328X</idno><imprint><date when="2005">2005</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Molecular brain research</title><title level="j" type="abbreviated">Mol. brain res.</title><idno type="ISSN">0169-328X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Emission tomography</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Tomoscintigraphie</term><term>Parkinson maladie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Over the past two decades, positron emission tomography (PET) has provided valuable insights into the mechanisms of nigrostriatal degeneration in Parkinson's disease (PD). 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